Molecular mimicry of brucella melitensis epitopes in mouse and human arthritis

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dc.contributor.authorBexeitov, Y. K.
dc.contributor.authorRamez, M
dc.contributor.authorForde, T. S.
dc.contributor.authorAdarichev, V. A.
dc.date.accessioned2015-10-21T09:26:49Z
dc.date.available2015-10-21T09:26:49Z
dc.date.issued2014
dc.description.abstractBrucellosis is one of the most frequent zoonosis worldwide. Infection is transferable to humans, where brucellosis is associated with high incidence of osteoarticular disease including osteomyelitis, arthritis and spondyloarthritis. Peripheral arthritis and sacroiliitis often develop in patients with no or low count of live Brucella. Recently, we demonstrated that mice develop spontaneous arthritis several weeks after acute infection when bacteria are already eradicated. We aim to decipher immune mechanism of the brucellosis-associated delayed arthritis that has not been elucidated so far.ru_RU
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/415
dc.language.isoenru_RU
dc.publisherNazarbayev Universityru_RU
dc.subjectbrucellosisru_RU
dc.subjectosteomyelitisru_RU
dc.subjectarthritisru_RU
dc.subjectspondyloarthritisru_RU
dc.subjectcytotoxic T cellsru_RU
dc.titleMolecular mimicry of brucella melitensis epitopes in mouse and human arthritisru_RU
dc.typeAbstractru_RU

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