The genetic history of admixture across inner Eurasia

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dc.contributor.authorJeong, Choongwon
dc.contributor.authorBalanovsky, Oleg
dc.contributor.authorLukianova, Elena
dc.contributor.authorKahbatkyzy, Nurzhibek
dc.contributor.authorFlegontov, Pavel
dc.contributor.authorZaporozhchenko, Valery
dc.contributor.authorImmell, Alexander
dc.contributor.authorWang, Chuan-Chao
dc.contributor.authorIxan, Olzhas
dc.contributor.authorKhussainova, Elmira
dc.contributor.authorBekmanov, Bakhytzhan
dc.contributor.authorZaibert, Victor
dc.contributor.authorLavryashina, Maria
dc.contributor.authorPocheshkhova, Elvira
dc.contributor.authorYusupov, Yuldash
dc.contributor.authorAgdzhoyan, Anastasiya
dc.contributor.authorKoshel, Sergey
dc.contributor.authorBukin, Andrei
dc.contributor.authorNymadawa, Pagbajabyn
dc.contributor.authorTurdikulova, Shahlo
dc.contributor.authorDalimova, Dilbar
dc.contributor.authorChurnosov, Mikhail
dc.contributor.authorSkhalyakho, Roza
dc.contributor.authorDaragan, Denis
dc.contributor.authorBogunov, Yuri
dc.contributor.authorBogunova, Anna
dc.contributor.authorShtrunov, Alexandr
dc.contributor.authorDubova, Nadezhda
dc.contributor.authorZhabagin, Maxat
dc.contributor.authorYepiskoposyan, Levon
dc.contributor.authorChurakov, Vladimir
dc.contributor.authorPislegin, Nikolay
dc.contributor.authorDamba, Larissa
dc.contributor.authorSaroyants, Ludmila
dc.contributor.authorDibirova, Khadizhat
dc.contributor.authorAtramentova, Lubov
dc.contributor.authorUtevska, Olga
dc.contributor.authorIdrisov, Eldar
dc.contributor.authorKamenshchikova, Evgeniya
dc.contributor.authorEvseeva, Irina
dc.contributor.authorMetspalu, Mait
dc.contributor.authorOutram, Alan K.
dc.contributor.authorRobbeets, Martine
dc.contributor.authorDjansugurova, Leyla
dc.contributor.authorBalanovska, Elena
dc.contributor.authorSchiffels, Stephan
dc.contributor.authorHaak, Wolfgang
dc.contributor.authorReich, David
dc.contributor.authorKrause, Johannes
dc.date.accessioned2019-12-12T06:08:31Z
dc.date.available2019-12-12T06:08:31Z
dc.date.issued2019-04
dc.descriptionhttps://www.ncbi.nlm.nih.gov/pubmed/31036896en_US
dc.description.abstractThe indigenous populations of inner Eurasia-a huge geographic region covering the central Eurasian steppe and the northern Eurasian taiga and tundra-harbour tremendous diversity in their genes, cultures and languages. In this study, we report novel genome-wide data for 763 individuals from Armenia, Georgia, Kazakhstan, Moldova, Mongolia, Russia, Tajikistan, Ukraine and Uzbekistan. We furthermore report additional damage-reduced genome-wide data of two previously published individuals from the Eneolithic Botai culture in Kazakhstan (~5,400 BP). We find that present-day inner Eurasian populations are structured into three distinct admixture clines stretching between various western and eastern Eurasian ancestries, mirroring geography. The Botai and more recent ancient genomes from Siberia show a decrease in contributions from so-called 'ancient North Eurasian' ancestry over time, which is detectable only in the northern-most 'forest-tundra' cline. The intermediate 'steppe-forest' cline descends from the Late Bronze Age steppe ancestries, while the 'southern steppe' cline further to the south shows a strong West/South Asian influence. Ancient genomes suggest a northward spread of the southern steppe cline in Central Asia during the first millennium BC. Finally, the genetic structure of Caucasus populations highlights a role of the Caucasus Mountains as a barrier to gene flow and suggests a post-Neolithic gene flow into North Caucasus populations from the steppe.en_US
dc.identifier.citationJeong, C., Balanovsky, O., Lukianova, E., Kahbatkyzy, N., Flegontov, P., Zaporozhchenko, V., … Krause, J. (2019). The genetic history of admixture across inner Eurasia. Nature Ecology & Evolution, 3(6), 966–976. https://doi.org/10.1038/s41559-019-0878-2en_US
dc.identifier.other10.1038/s41559-019-0878-2
dc.identifier.urihttp://nur.nu.edu.kz/handle/123456789/4427
dc.language.isoenen_US
dc.publisherNature Ecology & Evolutionen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectAdmixture modelingen_US
dc.subjectAdmixtureen_US
dc.subjectgenetic historyen_US
dc.subjectancient North Eurasianen_US
dc.titleThe genetic history of admixture across inner Eurasiaen_US
dc.typeArticleen_US
workflow.import.sourcescience

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