Genotyping Of M. Tuberculosis Clinical Isolates From New Cases Of Tuberculosis In Kazakhstan
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Date
2018-10-18
Authors
Akhmetova, А.
Akilzhanova, A.
Assatova, B.
Moldakhmetova, N.
Toksanbaeva, B.
Bismilda, V.
Chingissova, L.
Kozhamkulov, U.
Journal Title
Journal ISSN
Volume Title
Publisher
Nazarbayev University
Abstract
Tuberculosis (TB) remains a major health
problem in Kazakhstan. Despite of that the
rates of TB disease and mortality decreased
from 58,5/100000 and 4,1/100000 in 2015 to
52,7/100000 and 3,4/100000 in 2016
respectively, the rate of multidrug-resistant
TB (MDR-TB) increased from 12,2/100000
in 2014 to 13,5/100000 in 2015 [1];
MDR strains associated with resistance to
the main two first line anti-TB drugs –
isoniazid and rifampicin are the most
dangerous. 27 countries relate to high
MDR-TB burden countries, 15 of them in
the European region, including
Kazakhstan [2];
Methods of genotyping of M. tuberculosis
play important role in TB infection control.
There are more than 10 methods of
genotyping, MIRU-VNTR is one of the widely
used method in the world.
Description
Keywords
Tuberculosis (TB)
Citation
Akhmetova, А. et al. (2018) Genotyping Of M. Tuberculosis Clinical Isolates From New Cases Of Tuberculosis In Kazakhstan. Nazarbayev University