IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a casecontrol study

Thumbnail Image

Files

acs.jmedchem.9b00208.pdf (8.06 MB)

Date

2019-10-11

Authors

Sana, Mahjoub
Vera, Chayeb
Hedia, Zitouni
Rabeb M., Ghali
Haifa, Regaieg
Wassim Y., Almawi
Touhami, Mahjoub

Journal Title

Journal ISSN

Volume Title

Publisher

BMC MEDICAL GENETICS

Abstract

Background Associations between IKZF1 gene variants and Acute Lymphoblastic Leukemia (ALL) was recently reported. We examined whether the common IKZF1 polymorphisms rs4132601 T/G and rs111978267 A/G are associated with ALL among a Tunisian pediatric cohort. Methods This case-control study involved 170 patients with ALL and 150 control subjects. SNP genotyping was performed by TaqMan® SNP Genotyping Assay.

Description

Keywords

Acute lymphoblastic leukemia, Gene polymorphism, IKZF1, rs4132601, rs111978267

Citation

Mahjoub, S., Chayeb, V., Zitouni, H. et al. IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study. BMC Med Genet 20, 159 (2019) doi:10.1186/s12881-019-0900-1

URI

http://nur.nu.edu.kz/handle/123456789/4404

Collections

Articles