(Nazarbayev University, 2014) Merzhakupova, D.; Adilgozhina, G.; Kim, A.; Chao, W. T.; Kunz, J.
Rac1 activity is concentrated at the front of migrating cells where it initiates signaling
processes necessary for cell migration in normal and pathological situations. The signaling pathways
downstream of Rac1 are well characterized. However, how Rac1 activation is regulated to confer cell
movement is incompletely understood.